Dr. Wily declared himself the only true friend of robots and pledged that he would create a world where robots would rule over humans. Standing in the way of his conquest, however, was Dr. Light and his new combat robot Mega Man. Time and time again, Wily has concocted various diabolical schemes and built hundreds of robots to destroy the Blue Bomber and conquer the world, but has met with failure every single time. His resolve has never weakened, even after so many defeats, and he has always continued to plague Mega Man with new Robot Masters and deadly weapons with which to destroy his foe and mark his place in history as the world's greatest scientist.
Mega Man X
Prior to the start of the Mega Man X series, Dr. Wily had created a revolutionary new robot warrior: Zero. Zero was designed to outmatch Mega Man in every way, but unfortunately the doctor had trouble keeping his new creation under control. He sealed Zero within a diagnostic capsule and had intended to release him when he was sure it was safe to do so. However, Wily disappeared - supposedly died - before Zero was ready to be woken.
In the Mega Man X5 video game, there are many hints that indicate that Dr. Wily has played a key role in the game's events. Whether or not the doctor was truly alive during this time is unknown since he never made an on-screen appearance (except in one of Zero's memory flashes). If he was alive, one has to wonder how since the X series is set well over 100 years ahead of the Classic series.